MLT GlobeC-reactive protein (CRP)
Infectious Diseases · also called hs-CRP (high-sensitivity form)
What it measures
Measures an acute-phase protein made by the liver within hours of inflammation or infection. It helps detect and monitor infection, inflammatory disease and response to treatment.
Specimen and preparation
- Specimen: Serum or plasma
- Tube: Gold top
Reference range
| Group | Range |
|---|---|
| Adult | < 5 (some labs < 10) mg/L |
| hs-CRP low cardiac risk | < 1 mg/L |
| hs-CRP high cardiac risk | > 3 mg/L |
Reference ranges differ between laboratories, methods and populations. Always use the range printed on your own lab report.
Causes of high values
- Bacterial infection and sepsis (often > 100 mg/L)
- Tissue injury, surgery, burns
- Active rheumatoid arthritis and vasculitis
- Acute pancreatitis, myocardial infarction
Method
Immunoturbidimetry; latex agglutination (semi-quantitative)
Good to know
CRP rises and falls faster than ESR; SLE flares often show a normal CRP unless infection is present.
Related tests
📱 Practise with a timer, track your score and earn certificates in the free MLT Globe app – Google Play or practise online.