Red blood cell count (RBC)
Hematology · also called Erythrocyte count, RBC
What it measures
Counts the number of red cells per unit volume of blood. Used with hemoglobin and indices to classify anemias and erythrocytosis.
Specimen and preparation
- Specimen: Whole blood (EDTA)
- Tube: Lavender top
Reference range
| Group | Range |
|---|---|
| Adult male | 4.5–5.9 ×10¹²/L |
| Adult female | 4.0–5.2 ×10¹²/L |
| Child | 3.9–5.3 ×10¹²/L |
Reference ranges differ between laboratories, methods and populations. Always use the range printed on your own lab report.
Causes of high values
- Polycythemia vera
- Dehydration
- Chronic hypoxia
- Thalassemia trait (high count with small cells)
Causes of low values
- Anemias
- Hemorrhage
- Hemolysis
- Marrow failure
Method
Impedance or optical flow counting on a hematology analyzer
Good to know
A high RBC count with low MCV suggests thalassemia trait rather than iron deficiency (Mentzer index = MCV/RBC below 13). Cold agglutinins falsely lower the count.
Related tests
📱 Practise with a timer, track your score and earn certificates in the free MLT Globe app – Google Play or practise online.