Home › Lab tests › Neutrophils

Neutrophils

Hematology · also called Polymorphs, Segs, ANC, Absolute neutrophil count

What it measures

The most common white cell and the first line of defense against bacteria and fungi. Reported as a percentage and an absolute count; the absolute count guides infection risk.

Specimen and preparation

Specimen: Whole blood (EDTA)
Tube: Lavender top

Reference range

Group	Range
Adult (%)	40–75 %
Adult (absolute)	2.0–7.5 ×10⁹/L

Reference ranges differ between laboratories, methods and populations. Always use the range printed on your own lab report.

Causes of high values

Bacterial infection
Acute inflammation or tissue damage
Corticosteroids, stress, exercise
Chronic myeloid leukemia
Pregnancy

Causes of low values

Chemotherapy and certain drugs
Viral infection
Benign ethnic neutropenia
Aplastic anemia or marrow infiltration
Overwhelming sepsis

Method

Automated differential (flow cytometry/impedance) with manual smear review when flagged

Good to know

ANC below 0.5 ×10⁹/L is severe neutropenia with high infection risk. Toxic granulation and left shift on the smear support infection.

📱 Practise with a timer, track your score and earn certificates in the free MLT Globe app – Google Play or practise online.