Fibrin/fibrinogen degradation products (FDP)

What it measures

Measures fragments released when plasmin breaks down fibrin and fibrinogen. It supports the diagnosis of DIC and other states of increased fibrinolysis.

Specimen and preparation

• Specimen: Citrated plasma or special serum tube with antifibrinolytic
• Tube: Light_blue top

Reference range

Reference ranges differ between laboratories, methods and populations. Always use the range printed on your own lab report.

Causes of high values

• Disseminated intravascular coagulation
• Venous thromboembolism
• Thrombolytic therapy
• Primary fibrinolysis
• Liver disease, recent surgery

Method

Latex agglutination (semi-quantitative) or immunoturbidimetry

Good to know

Unlike D-dimer, FDP also rises with breakdown of fibrinogen alone. D-dimer is more specific for fibrin formation.

Related tests