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749 practice MCQs for the QCHP medical laboratory exam. Level: Intermediate.

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Q321EasyEnterobacterales

Stool from a patient with bacillary dysentery due to Shigella typically contains:

Answer: C. Blood, mucus and many pus cells

Shigella invades the colonic mucosa, giving small-volume stools with blood, mucus and neutrophils.

ID MG-EBAC-0047 · Found a mistake? Report it
Q322EasyNon-fermenters & other GNR

Chlamydia trachomatis cannot be grown on ordinary agar media because it:

Answer: C. Is an obligate intracellular bacterium

Chlamydiae depend on host-cell energy, so they are grown only in cell culture or detected by NAAT.

ID MG-EBAC-0051 · Found a mistake? Report it
Q323EasyNeisseria & fastidious

On a Gram stain, Neisseria species typically appear as:

Answer: C. Gram-negative kidney-bean-shaped diplococci

Neisseria are Gram-negative cocci in pairs with their flat sides facing, giving a kidney-bean shape.

ID MG-EBAC-0059 · Found a mistake? Report it
Q324EasyNeisseria & fastidious

Neisseria gonorrhoeae attaches to mucosal epithelial cells mainly by means of:

Answer: B. Pili (fimbriae)

Gonococcal pili mediate adherence to urethral and cervical cells; Neisseria have no flagella and form no spores.

ID MG-EBAC-0066 · Found a mistake? Report it
Q325EasyAnaerobes

Which anaerobe is most frequently isolated from intra-abdominal abscesses and other anaerobic infections?

Answer: D. Bacteroides fragilis

B. fragilis is the most commonly isolated anaerobic pathogen, especially after bowel perforation.

ID MG-EBAC-0072 · Found a mistake? Report it
Q326EasyMycobacteria

Patients taking rifampicin for tuberculosis should be told that the drug commonly:

Answer: A. Turns urine and other body fluids orange-red

Rifampicin is a red-orange pigment that colours urine, sweat and tears; this is harmless.

ID MG-EBAC-0085 · Found a mistake? Report it
Q327EasyMycobacteria

Which of these is a first-line anti-tuberculosis drug?

Answer: B. Ethambutol

Standard first-line TB treatment uses isoniazid, rifampicin, pyrazinamide and ethambutol.

ID MG-EBAC-0086 · Found a mistake? Report it
Q328EasyMycobacteria

Multidrug-resistant tuberculosis (MDR-TB) is defined as resistance to at least:

Answer: C. Isoniazid and rifampicin

MDR-TB means resistance to at least isoniazid and rifampicin, the two most important first-line drugs.

ID MG-EBAC-0087 · Found a mistake? Report it
Q329EasyMycobacteria

A Mantoux tuberculin skin test is read how long after injection?

Answer: D. 48–72 hours

The test measures delayed-type hypersensitivity, so the induration is read after 48–72 hours.

ID MG-EBAC-0088 · Found a mistake? Report it
Q330EasyIntestinal protozoa

Humans become infected with Entamoeba histolytica by swallowing which stage?

Answer: C. Mature four-nucleated cyst

The mature quadrinucleate cyst survives stomach acid and excysts in the intestine; trophozoites are destroyed outside the body and by gastric acid.

ID MG-EPAR-0001 · Found a mistake? Report it
Q331EasyCestodes (tapeworms)

Why must spillage of hydatid cyst fluid be avoided during aspiration or surgery?

Answer: C. It can cause anaphylaxis and spread protoscolices

Cyst fluid is highly antigenic and contains protoscolices, so leakage can cause anaphylactic shock and secondary cysts.

ID MG-EPAR-0017 · Found a mistake? Report it
Q332EasyCestodes (tapeworms)

The segments that make up the body of a tapeworm are called:

Answer: A. Proglottids

The strobila is a chain of proglottids; the scolex is the attachment organ at the head end.

ID MG-EPAR-0019 · Found a mistake? Report it
Q333EasyMycology

Fungal hyphae with regular cross-walls are described as:

Answer: B. Septate

Septate hyphae have cross-walls (septa), as in Aspergillus and dermatophytes; Mucorales have mostly aseptate hyphae.

ID MG-EMYC-0002 · Found a mistake? Report it
Q334EasyMycology

Routine fungal cultures for moulds are usually incubated at:

Answer: B. 25–30 °C

Most moulds grow best at 25–30 °C; 37 °C is used additionally to show the yeast phase of dimorphic fungi.

ID MG-EMYC-0010 · Found a mistake? Report it
Q335EasyMycology

Yeasts such as Candida reproduce asexually mainly by:

Answer: C. Budding

Yeasts form buds (blastoconidia) that pinch off from the parent cell.

ID MG-EMYC-0011 · Found a mistake? Report it
Q336EasyMycology

Candida albicans is best described as:

Answer: A. A commensal yeast that causes opportunistic infection

C. albicans is normal flora of the mouth, gut and vagina and causes disease when defences or normal flora are disturbed.

ID MG-EMYC-0017 · Found a mistake? Report it
Q337EasyHepatitis viruses

Against which of these viruses is there currently no licensed vaccine in routine use?

Answer: B. Hepatitis C virus

Hepatitis C is prevented by blood safety measures and treated with antivirals, but no vaccine exists; hepatitis A, hepatitis B and measles vaccines are routinely used.

ID MG-EVIR-0006 · Found a mistake? Report it
Q338EasyRespiratory viruses

SARS-CoV-2, the cause of COVID-19, belongs to which virus family?

Answer: B. Coronaviridae

SARS-CoV-2 is an enveloped positive-sense RNA betacoronavirus of the family Coronaviridae.

ID MG-EVIR-0014 · Found a mistake? Report it
Q339EasyArboviruses & zoonotic viruses

Chikungunya fever is characterised especially by:

Answer: D. Severe, often long-lasting joint pain

The name comes from a Makonde word for 'that which bends up', reflecting the disabling arthralgia.

ID MG-EVIR-0020 · Found a mistake? Report it
Q340MediumImmune system principles

Which statement about antibody structure is FALSE?

Answer: A. The light-chain type determines the class

Class (isotype) depends on the heavy chain; kappa or lambda light chains occur in every class. IgG has two identical binding sites.

ID LG-IMM-0013 · Found a mistake? Report it
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