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Virology: Hepatitis viruses – page 3

42 Virology MCQs on Hepatitis viruses with answers and explanations.

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Q41HardHepatitis viruses

Hepatitis D virus is placed in which genus under current taxonomy?

Answer: C. Deltavirus (family Kolmioviridae)

HDV is the type species of genus Deltavirus, now in family Kolmioviridae. HAV is a hepatovirus, HBV an orthohepadnavirus, and HCV a hepacivirus.

ID LG-VIR-0138 · Found a mistake? Report it
Q42HardHepatitis viruses

A chronic HBV patient is HBeAg negative and anti-HBe positive, but HBV DNA is high and ALT is raised. The most likely explanation is:

Answer: D. A precore or core promoter mutant that makes little or no HBeAg

Precore or core promoter mutations reduce HBeAg production while the virus keeps replicating. HBV DNA, not HBeAg, reflects replication in these patients.

ID MG-VIR-0009 · Found a mistake? Report it
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