MLT GlobeBasic Pathology: Immunopathology
4 Basic Pathology MCQs on Immunopathology with answers and explanations.
In rheumatoid arthritis, immune reactions against self antigens cause persistent inflammation and joint damage. This disease group is termed:
Answer: C. Autoimmune disease
Autoimmune diseases result from self-perpetuating immune responses against the body's own antigens, e.g., rheumatoid arthritis and multiple sclerosis.
ID LG-PAT-0065 · Found a mistake? Report it
In normal adult peripheral blood, which lymphocyte lineage is most numerous?
Answer: D. T cells
T cells make up about 60 to 80% of circulating lymphocytes. B cells and NK cells are minor fractions, and plasma cells are rarely seen in blood.
ID LG-PAT-0250 · Found a mistake? Report it
Bronchospasm within minutes of allergen exposure in atopic asthma is mediated mainly by:
Answer: D. IgE-sensitised mast cells (type I hypersensitivity)
Allergen cross-links IgE on mast cells, releasing histamine and leukotrienes: an immediate type I reaction.
ID LG-PAT-0354 · Found a mistake? Report it
Chronic inflammation due to excessive immune responses to common environmental substances, such as in bronchial asthma, is typical of:
Answer: D. Allergic diseases
Allergic diseases result from exaggerated immune reactions to harmless environmental antigens. Autoimmune diseases target self antigens.
ID LG-PAT-0490 · Found a mistake? Report it
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