MLT GlobeCalcitonin
Thyroid · also called Thyrocalcitonin
What it measures
Calcitonin is a hormone secreted by the parafollicular C cells of the thyroid. It is the tumour marker for medullary thyroid carcinoma and is used in diagnosis, family screening and follow-up.
Specimen and preparation
- Specimen: Serum or lithium-heparin plasma
- Tube: Gold top
- Preparation: Fasting sample; place on ice and separate quickly.
Reference range
| Group | Range |
|---|---|
| Adult male | <10 pg/mL |
| Adult female | <5 pg/mL |
Reference ranges differ between laboratories, methods and populations. Always use the range printed on your own lab report.
Causes of high values
- Medullary thyroid carcinoma
- C-cell hyperplasia (MEN 2)
- Chronic kidney disease
- Proton pump inhibitors
- Neuroendocrine tumours
- Smoking
Method
Chemiluminescent immunoassay
Good to know
Pair with CEA in medullary thyroid carcinoma follow-up; doubling time predicts outcome.
Related tests
📱 Practise with a timer, track your score and earn certificates in the free MLT Globe app – Google Play or practise online.